SAVARAJ, N: search on Z-Library

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1

Design of Antineoplastic Agents Based on the “2-Phenylnaphthalene-Type” Structural Pattern. 4. Synthesis and Biological Activity of 2-Chloro-3-(substituted phenoxy)-1,4-naphthoquinones and Related 5,8-Dihydroxy-1,4-naphthoquinones

Chang, He-Xi, Chou, Ting-Chao, Savaraj, Niramol, Liu, Leroy F., Yu, Chiang, Cheng, C. C.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 146 KB

english, 1999

2

Design of antineoplastic agents on the basis of the 2-phenylnaphthalene-type structural pattern. 2. Synthesis and biological activity studies of benzo[b]naphtho[2,3-d]furan-6,11-dione derivatives

Cheng, C. C., Dong, Qing, Liu, Dun Fu, Luo, Yi Lin, Liu, Leroy F., Chen, Allan Y., Yu, Chiang, Savaraj, Niramol, Chou, Ting Chao

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 640 KB

english, 1993

3

Differential Sensitivity to 2-Deoxy-D-glucose Between Two Pancreatic Cell Lines Correlates With GLUT-1 Expression

Maher, Johnathan C, Savaraj, Niramol, Priebe, Waldemar, Liu, Huaping, Lampidis, Theodore J

Journal:

Year:

2005

Language:

english

File:

PDF, 345 KB

english, 2005

4

Design of antineoplastic agents based on the ‘2-phenylnaphthalene-type’ structural pattern—synthesis and biological activity studies of 11H-indolo[3.2-c]quinoline derivatives

Ling He, He-Xi Chang, Ting-Chao Chou, Niramol Savaraj, C.C Cheng

Journal:

European Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 260 KB

english, 2003

5

A phase I, II study of high-dose 5-fluorouracil and high-dose leucovorin with low-dose phosphonacetyl-L-aspartic acid in patients with advanced malignancies

Bach Ardalan, Kasi S. Sridhar, Pasquale Benedetto, Stephen Richman, Stuart Waldman, Louise Morrell, Lynn Feun, Niramol Savaraj, Miguel Fodor, Alan Livingstone

Journal:

Year:

1991

Language:

english

File:

PDF, 454 KB

english, 1991

6

2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

Haibin Xi, Metin Kurtoglu, Huaping Liu, Medhi Wangpaichitr, Min You, Xiongfei Liu, Niramol Savaraj, Theodore J. Lampidis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 711 KB

english, 2011

7

High-performance liquid chromatographic separation and quantitation of benzisoquinolinedione (Nafidimide) from biological fluids

Katherine Lu, Nimarol Savaraj, Robert A. Newman

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1985

Language:

english

File:

PDF, 340 KB

english, 1985

8

Pilot Study of Estramustine Added to Radiosurgery and Radiotherapy for Treatment of High Grade Glioma

Howard Landy, Arnold Markoe, Priscilla Potter, Garrett Lasalle, Angela Marini, Niramol Savaraj, Isildinha Reis, Deborah Heros, Medhi Wangpaichitr, Lynn Feun

Journal:

Journal of Neuro-Oncology

Year:

2004

Language:

english

File:

PDF, 202 KB

english, 2004

9

Glutathione Depletion-Induced Thymidylate Insufficiency for DNA Repair Synthesis

Khingkan Lertratanangkoon, Niramol Savaraj, Joseph M. Scimeca, Mary L. Thomas

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 789 KB

english, 1997

10

Doxorubicin- and Daunorubicin-Glutathione Conjugates, but Not Unconjugated Drugs, Competitively Inhibit Leukotriene C4Transport Mediated byMRP/GS-XPump

Waldemar Priebe, Marta Krawczyk, M.Tien Kuo, Yoshiaki Yamane, Niramol Savaraj, Toshihisa Ishikawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 114 KB

english, 1998

11

Overcoming cisplatin resistance by mTOR inhibitor in lung cancer

Chunjing Wu, Medhi Wangpaichitr, Lynn Feun, Marcus Tien Kuo, Carlos Robles, Theodore Lampidis, Niramol Savaraj

Journal:

Molecular Cancer

Year:

2005

Language:

english

File:

PDF, 1.09 MB

english, 2005

12

Regulation of the high-affinity copper transporter

Liang, Zheng Dong, Long, Yan, Chen, Helen H. W., Savaraj, Niramol, Kuo, Macus Tien

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2014

Language:

english

File:

PDF, 783 KB

english, 2014

13

A Pilot Clinical and Pharmacological Study of Intra-Arterial Infusion of Thiotepa

Savaraj, Niramol, Feun, Lynn G., Blyden, Gershwin, Yrizarry, Jose M., Hsiang, Juei-Tang G., Curtas, Jaime, Waldman, Stuart, Post, Judith D., Benedetto, Pasquale, Landy, Howard, Guerra, Jorge J.

Journal:

Cancer Biotherapy

Year:

1993

Language:

english

File:

PDF, 689 KB

english, 1993

14

Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines

Wangpaichitr, M., Savaraj, N., Maher, J., Kurtoglu, M., Lampidis, T. J.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 687 KB

english, 2008

15

Specificity Protein 1 (Sp1) Oscillation Is Involved in Copper Homeostasis Maintenance by Regulating Human High-Affinity Copper Transporter 1 Expression

Liang, Z. D., Tsai, W.-B., Lee, M.-Y., Savaraj, N., Kuo, M. T.

Journal:

Molecular Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.20 MB

english, 2012

16

Clinical and Pharmacological Study of Intrahepatic Artery Infusion of Thiotepa

Feun, Lynn G., Blyden, Gershwin, Yrizarry, Jose, Dorvil, Marie, Waldman, Stuart, Benedetto, Pasquale, Donnelly, Elizabeth, Curtas, Jaime, George, Martine, Savaraj, Niramol

Journal:

Cancer Biotherapy

Year:

1993

Language:

english

File:

PDF, 644 KB

english, 1993

17

Phase II trial of piritrexim in metastatic melanoma using intermittent, low-dose administration.

Feun, L G, Gonzalez, R, Savaraj, N, Hanlon, J, Collier, M, Robinson, W A, Clendeninn, N J

Journal:

Journal of Clinical Oncology

Year:

1991

Language:

english

File:

PDF, 335 KB

english, 1991

18

Intracerebral penetration and tissue distribution of 2,5-diaziridinyl 3,6-bis(carboethoxyamino) 1,4-benzoquinone (AZQ, NSC-182986)

Niramol Savaraj, Katherine Lu, Lynn G. Feun, Milam E. Leavens, David Stewart, Michael A. Burgess, Robert S. Benjamin, Ti Li Loo

Journal:

Journal of Neuro-Oncology

Year:

1983

Language:

english

File:

PDF, 344 KB

english, 1983

19

Phase I clinical trial of intralesional or intraventricular leukocyte interferon for intracranial malignancies

Eugenie AMT Obbens, Lynn G Feun, Milam E Leavens, Niramol Savaraj, David J Stewart, Jordan U Gutterman

Journal:

Journal of Neuro-Oncology

Year:

1985

Language:

english

File:

PDF, 488 KB

english, 1985

20

The pharmacologic fate of 2,5-diaziridinyl-3,6-bis(carboethoxyamino) 1,4-benzoquinone (AZQ NSC-182986) by intracarotid or intravenous administration in beagles

Lynn G. Feun, Niramol Savaraj, Katherine Lu, Zhengang Guo, L. Gilbert Raulston, Robert S. Benjamin, William S. Fields, Ti Li Loo

Journal:

Journal of Neuro-Oncology

Year:

1983

Language:

english

File:

PDF, 379 KB

english, 1983

21

Correlation of a unique 220-kDa protein with vitamin D sensitivity in glioma cells

Jiangying Zou, Howard Landy, Lynn Feun, Rong Xu, Theodore Lampidis, Chun Jing Wu, A.J Furst, Niramol Savaraj

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 313 KB

english, 2000

22

ρ0 tumor cells: a model for studying whether mitochondria are targets for rhodamine 123, doxorubicin, and other drugs

Yan-Ping Hu, Carlos T Moraes, Niramol Savaraj, Waldemar Priebe, Theodore J Lampidis

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 792 KB

english, 2000

23

TRAIL induces autophagic protein cleavage through caspase activation in melanoma cell lines under arginine deprivation

You, Min, Savaraj, Niramol, Kuo, Macus T., Wangpaichitr, Medhi, Varona-Santos, Javier, Wu, Chunjing, Nguyen, Dao M., Feun, Lynn

Journal:

Molecular and Cellular Biochemistry

Year:

2013

Language:

english

File:

PDF, 626 KB

english, 2013

24

Phase-I Trial of Intracarotid BCNU and Cisplatin in Patients with Malignant Intracerebral Tumors

FEUN, LYNN G., WALLACE, SIDNEY, YUNG, WAI-KWAN A., LEE, YA YEN, LEAVENS, MILAM E., MOSER, RICHARD, SAVARAJ, NIRAMOL, BURGESS, M. ANDREW, PLAGER, CARL, BENJAMIN, ROBERT S., TANG, ROSA A., MAVLIGIT, GIO

Journal:

Cancer Drug Delivery

Year:

1984

Language:

english

File:

PDF, 783 KB

english, 1984

25

The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma

Thongkum, Angkana, Wu, Chunjing, Li, Ying-Ying, Wangpaichitr, Medhi, Navasumrit, Panida, Parnlob, Varabhorn, Sricharunrat, Thaniya, Bhudhisawasdi, Vajarabhongsa, Ruchirawat, Mathuros, Savaraj, Niramol

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 9.50 MB

english, 2017

26

Intracarotid VP-16 in malignant brain tumors

Lynn G. Feun, YaYen Lee, Wai-Kwan Alfred Yung, Niramol Savaraj, Sidney Wallace

Journal:

Journal of Neuro-Oncology

Year:

1987

Language:

english

File:

PDF, 318 KB

english, 1987

27

Osteogenic sarcoma arising adjacent to a long-standing ameloblastoma: A case report

Lynn G. Feun, Jorge Albores-Saavedra, Niramol Savaraj

Journal:

Oral Surgery, Oral Medicine, Oral Pathology

Year:

1991

Language:

english

File:

PDF, 1.72 MB

english, 1991

28

Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1 /Sp4

Tsai, W.-B., Aiba, I., Lee, S.-y., Feun, L., Savaraj, N., Kuo, M. T.

Journal:

Molecular Cancer Therapeutics

Year:

2009

Language:

english

File:

PDF, 551 KB

english, 2009

29

Mechanistic Basis for Overcoming Platinum Resistance Using Copper Chelating Agents

Liang, Z. D., Long, Y., Tsai, W.-B., Fu, S., Kurzrock, R., Gagea-Iurascu, M., Zhang, F., Chen, H. H. W., Hennessy, B. T., Mills, G. B., Savaraj, N., Kuo, M. T.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.75 MB

english, 2012

30

DIFFERENTIAL SENSITIVITY AMONG 3 HUMAN SUBPOPULATIONS IN RESPONSE TO 4-NITROQUINOLINE-1-OXIDE AND TO BLEOMYCIN

HSU, TC, FEUN, L, TRIZNA, Z, SAVARAJ, N, SHIRLEY, LR, FURLONG, CL, SCHANTZ, SP, WEBER, RS, SHEN, TJ, KUCUK, O

Journal:

International Journal of Oncology

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

31

Central nervous system (CNS) penetration of homoharringtonine (HHT)

Niramol Savaraj, Lynn G. Feun, Katherine Lu, Maam Leavens, Richard Moser, William S. Fields, Ti Li Loo

Journal:

Journal of Neuro-Oncology

Year:

1987

Language:

english

File:

PDF, 295 KB

english, 1987

32

Phase II study of homoharringtonine in patients with recurrent primary malignant central nervous system tumors

Lynn G. Feun, Niramol Savaraj, Howard Landy, Howard Levin, Theodore Lampidis

Journal:

Journal of Neuro-Oncology

Year:

1990

Language:

english

File:

PDF, 337 KB

english, 1990

33

Two Multidrug-Resistant Friend Leukemic Cell Lines Selected with Different Drugs Exhibit Overproduction of Different P-Glycoproteins

Savaraj, Niramol, Lampidis, T. J., Zhao, Ji-Ying, Wu, Chun Jing, Teeter, Larry D., Kuo, M. Tien

Journal:

Cancer Investigation

Year:

1994

Language:

english

File:

PDF, 680 KB

english, 1994

34

Topoisomerase I Inhibitors in the Treatment of Primary CNS Malignancies: An Update on Recent Trends

P. Sasine, Joshua, Savaraj, Niramol, G. Feun, Lynn

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 267 KB

english, 2010

35

Relationship of Metabolic Alterations and PD-L1 Expression in Cisplatin Resistant Lung Cancer

M, Wangpaichitr, H, Kandemir, YY, Li, C, Wu, DJM, Nguyen, LG, Feun, MT, Kuo, N, Savaraj

Journal:

Cell & Developmental Biology

Year:

2017

Language:

english

File:

PDF, 660 KB

english, 2017

36

Pilot Study of PCNU and Cranial Radiation Therapy in the Treatment of Patients with Malignant Gliomas

Feun, Lynn G., Maor, Moshe, Stewart, David J., Leavens, Milam E., Savaraj, Niramol, Bodey, Gerald P.

Journal:

Year:

1990

File:

PDF, 557 KB

1990

37

Detection of 11q13 amplification as the origin of a homogeneously staining region in small cell lung cancer by chromosome microdissection

Jia Xu, Tina Tyan, Edward Cedrone, Niramol Savaraj, Nancy Wang

Journal:

Genes, Chromosomes and Cancer

Year:

1996

Language:

english

File:

PDF, 640 KB

english, 1996

38

Expression of heavy subunit of γ-glutamylcysteine synthetase (γ-GCSh) in human colorectal carcinoma

Shigeru Tatebe, Hitoshi Unate, Frank A. Sinicrope, Takashi Sakatani, Kenji Sugamura, Masato Makino, Hisao Ito, Niramol Savaraj, Nobuaki Kaibara, M. Tien Kuo

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 872 KB

english, 2002

39

Roles of reactive oxygen species in hepatocarcinogenesis and drug resistance gene expression in liver cancers

M. Tien Kuo, Niramol Savaraj

Journal:

Molecular Carcinogenesis

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

40

Aminoglutethimide in the management of metastatic breast cancer

Niramol Savaraj, Michael B. Troner

Journal:

Pediatric Blood & Cancer

Year:

1980

Language:

english

File:

PDF, 1.75 MB

english, 1980

41

Drug resistance in brain tumors

Lynn G. Feun, Niramol Savaraj, Howard J. Landy

Journal:

Journal of Neuro-Oncology

Year:

1994

Language:

english

File:

PDF, 1.01 MB

english, 1994

42

Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro

You, Min, Varona-Santos, Javier, Singh, Samer, Robbins, David J., Savaraj, Niramol, Nguyen, Dao M.

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

43

Clinical pharmacology of 2,5′-diaziridinyl-3,6-biscarboethoxyamino-1,4-benzoquinone (AZQ)

Lu, Katherine, Savaraj, Niramol, Yap, Boh Seng, Bedikian, Agop Y., Feun, Lynn, Benjamin, Robert S., Loo, Ti Li

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1983

Language:

english

File:

PDF, 342 KB

english, 1983

44

Tumor Penetration of AMSA in Man

Zhengang, Guo, Savaraj, Niramol, Feun, Lynn G., Lu, Katherine, Stewart, David J., Luna, Mario, Benjamin, Robert S., Loo, Ti Li

Journal:

Cancer Investigation

Year:

1983

Language:

english

File:

PDF, 279 KB

english, 1983

45

Elevated Glutathione Levels Confer Cellular Sensitization to Cisplatin Toxicity by Up-Regulation of Copper Transporter hCtr1

Chen, H. H. W., Song, I.-S., Hossain, A., Choi, M.-K., Yamane, Y., Liang, Z. D., Lu, J., Wu, L. Y.-H., Siddik, Z. H., Klomp, L. W. J., Savaraj, N., Kuo, M. T.

Journal:

Molecular Pharmacology

Year:

2008

Language:

english

File:

PDF, 479 KB

english, 2008

46

Spinal Cord Compression Produced by Osteomyelitis Mimicking Spinal Epidural Metastasis

Feun, Lynn G., Savaraj, Niramol, Bujnoski, Joanne, Nadeem, Saba

Journal:

American Journal of Clinical Oncology

Year:

1992

File:

PDF, 474 KB

1992

47

Early-stage non-small-cell lung cancer: overview of adjuvant chemotherapy and promising advances

Matsangou, Maria, Santos, Edgardo S, Raez, Luis E, Gomez, Jorge E, Dinh, Vy, Savaraj, Niramol

Journal:

Lung Cancer Management

Year:

2014

Language:

english

File:

PDF, 1.59 MB

english, 2014

48

Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer

Nguyen, Dan JM, Theodoropoulos, George, Li, Ying-Ying, Wu, Chunjing, sha, Wei, Feun, Lynn G., Lampidis, Theodore J., Savaraj, Niramol, Wangpaichitr, Medhi

Journal:

Molecular Cancer Research

Year:

2019

Language:

english

File:

PDF, 1.45 MB

english, 2019

49

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors

Kuo, Macus Tien, Long, Yan, Tsai, Wen-Bin, Li, Ying-Ying, Chen, Helen H.W., Feun, Lynn G., Savaraj, Niramol

Journal:

Translational Oncology

Year:

2020

File:

PDF, 2.00 MB

2020

50

A phase II trial of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (PCNU, NSC 95466) in recurrent malignant brain tumors

Lynn G. Feun, David J. Stewart, Milam E. Leavens, M. Andrew Burgess, Niramol Savaraj, Robert S. Benjamin, G. P. Bodey

Journal:

Journal of Neuro-Oncology

Year:

1983

Language:

english

File:

PDF, 264 KB

english, 1983

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